IL-37 is highly expressed in T(reg) cells of melanoma patients and enhanced by melanoma cell secretome

Immune suppression is one of the 10 hallmarks of cancer. Interleukin-37 (IL-37), a member of the IL-1 family, inhibits both innate and adaptive immunity, and has been shown to modulate immune responses in various disease conditions. Yet, IL-37 has rarely been investigated in cancer patients, and its...

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Bibliographic Details
Published in:Mol Carcinog
Main Authors: Osborne, Douglas G., Domenico, Joanne, Luo, Yuchun, Reid, Anna L., Amato, Carol, Zhai, Zili, Gao, Dexiang, Ziman, Melanie, Dinarello, Charles A., Robinson, William A., Fujita, Mayumi
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692223/
https://ncbi.nlm.nih.gov/pubmed/31099111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23044
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