Diversity of Bacteria Exhibiting Bile Acid-inducible 7α-dehydroxylation Genes in the Human Gut

The secondary bile acids deoxycholic acid (DCA) and lithocholic acid (LCA), formed by gut microbiota from primary bile acids via a multi-step 7α-dehydroxylation reaction, have wide-ranging effects on host metabolism and play an important role in health and disease. A few 7α-dehydroxylating strains h...

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Detalles Bibliográficos
Publicado en:Comput Struct Biotechnol J
Autores principales: Vital, Marius, Rud, Tatjana, Rath, Silke, Pieper, Dietmar H., Schlüter, Dirk
Formato: Artigo
Lenguaje:Inglês
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Short Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692061/
https://ncbi.nlm.nih.gov/pubmed/31428294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.07.012
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