Equine arteritis virus long-term persistence is orchestrated by CD8(+) T lymphocyte transcription factors, inhibitory receptors, and the CXCL16/CXCR6 axis

Equine arteritis virus (EAV) has the unique ability to establish long-term persistent infection in the reproductive tract of stallions and be sexually transmitted. Previous studies showed that long-term persistent infection is associated with a specific allele of the CXCL16 gene (CXCL16S) and that p...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Carossino, Mariano, Dini, Pouya, Kalbfleisch, Theodore S., Loynachan, Alan T., Canisso, Igor F., Cook, R. Frank, Timoney, Peter J., Balasuriya, Udeni B. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692045/
https://ncbi.nlm.nih.gov/pubmed/31356622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007950
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