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Cap-Independent mRNA Translation Is Upregulated in Long-Lived Endocrine Mutant Mice

It has been hypothesized that transcriptional changes associated with lower mTORC1 activity in mice with reduced levels of Growth Hormone and Insulin-like Growth Factor 1 are responsible for the longer healthy lifespan of these mutant mice. Cell lines and tissues from these mice show alterations in...

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Detalhes bibliográficos
Publicado no:J Mol Endocrinol
Main Authors: Ozkurede, Ulas, Kala, Rishabh, Johnson, Cameron, Shen, Ziqian, Miller, Richard A., Garcia, Gonzalo G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691957/
https://ncbi.nlm.nih.gov/pubmed/31357177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JME-19-0021
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