Targeted Next-Generation Sequencing Identifies Novel Sequence Variations of Genes Associated with Nonobstructive Azoospermia in the Han Population of Northeast China

BACKGROUND: This study aimed to screen common and low-frequency variants of nonobstructive azoospermia (NOA)-associated genes, and to construct a database for NOA-associated single nucleotide variants (SNVs). MATERIAL/METHODS: Next-generation sequencing of 466 NOA-associated genes was performed in 3...

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Dettagli Bibliografici
Pubblicato in:Med Sci Monit
Autori principali: Liu, Xiangyin, Xi, Qi, Li, Leilei, Wang, Qiyuan, Jiang, Yuting, Zhang, Hongguo, Liu, Ruizhi, Wang, Ruixue
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Scientific Literature, Inc. 2019
Soggetti:
Clinical Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691750/
https://ncbi.nlm.nih.gov/pubmed/31377750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.915375
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