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Long-term safety and efficacy of sarilumab plus methotrexate on disease activity, physical function and radiographic progression: 5 years of sarilumab plus methotrexate treatment

OBJECTIVE: In MOBILITY (NCT01061736), sarilumab significantly reduced disease activity, improved physical function and inhibited radiographic progression at week 52 versus placebo in patients with rheumatoid arthritis (RA) and an inadequate response to methotrexate. We report 5-year safety, efficacy...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RMD Open
Prif Awduron: Genovese, Mark C, van der Heijde, Désirée, Lin, Yong, St John, Gregory, Wang, Sheldon, van Hoogstraten, Hubert, Gómez-Reino, Juan José, Kivitz, Alan, Maldonado-Cocco, José Antonio, Seriolo, Bruno, Stanislav, Marina, Burmester, Gerd R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMJ Publishing Group 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691511/
https://ncbi.nlm.nih.gov/pubmed/31452928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2018-000887
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