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In silico Guided Drug Repurposing: Discovery of New Competitive and Non-competitive Inhibitors of Falcipain-2

Malaria is among the leading causes of death worldwide. The emergence of Plasmodium falciparum resistant strains with reduced sensitivity to the first line combination therapy and suboptimal responses to insecticides used for Anopheles vector management have led to renewed interest in novel therapeu...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Alberca, Lucas N., Chuguransky, Sara R., Álvarez, Cora L., Talevi, Alan, Salas-Sarduy, Emir
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691349/
https://ncbi.nlm.nih.gov/pubmed/31448257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00534
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