Opposing roles of endothelial and leukocyte-expressed IL-7Rα in the regulation of psoriasis-like skin inflammation

The interleukin 7 receptor alpha chain (IL-7Rα) is predominately expressed by lymphocytes, and activation by its ligand IL-7 supports the development and maintenance of T cells and boosts T-cell mediated immunity. We recently reported that lymphatic endothelial cells (LECs) in dermal lymphatics also...

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Udgivet i:Sci Rep
Main Authors: Vranova, Martina, Friess, Mona C., Haghayegh Jahromi, Neda, Collado-Diaz, Victor, Vallone, Angela, Hagedorn, Olivia, Jadhav, Maria, Willrodt, Ann-Helen, Polomska, Anna, Leroux, Jean-Christophe, Proulx, Steven T., Halin, Cornelia
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691132/
https://ncbi.nlm.nih.gov/pubmed/31406267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48046-y
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