Virus-Specific Secondary Plasma Cells Produce Elevated Levels of High-Avidity Antibodies but Are Functionally Short Lived

Most vaccines aim at inducing durable antibody responses and are designed to elicit strong B cell activation and plasma cell (PC) formation. Here we report characteristics of a recently described secondary PC population that rapidly originates from memory B cells (MBCs) upon challenge with virus-lik...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Krueger, Caroline C., Thoms, Franziska, Keller, Elsbeth, Vogel, Monique, Bachmann, Martin F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691049/
https://ncbi.nlm.nih.gov/pubmed/31447844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01831
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