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Staurosporine from Streptomyces sanyensis activates Programmed Cell Death in Acanthamoeba via the mitochondrial pathway and presents low in vitro cytotoxicity levels in a macrophage cell line

Recently, the search for novel therapeutic agents against Acanthamoeba species has been focused on the evaluation of natural resources. Among them, marine microorganisms have risen as a source of bioactive compounds with the advantage of the ability to obtain unlimited and constant amounts of the co...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cartuche, Luis, Sifaoui, Ines, Cruz, Darío, Reyes-Batlle, María, López-Arencibia, Atteneri, Javier Fernández, José, Díaz-Marrero, Ana R., Piñero, José E., Lorenzo-Morales, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690954/
https://ncbi.nlm.nih.gov/pubmed/31406269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48261-7
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