Hydrogen sulfide perturbs mitochondrial bioenergetics and triggers metabolic reprogramming in colon cells

Unlike most other tissues, the colon epithelium is exposed to high levels of H(2)S derived from gut microbial metabolism. H(2)S is a signaling molecule that modulates various physiological effects. It is also a respiratory toxin that inhibits complex IV in the electron transfer chain (ETC). Colon ep...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Libiad, Marouane, Vitvitsky, Victor, Bostelaar, Trever, Bak, Daniel W., Lee, Ho-Joon, Sakamoto, Naoya, Fearon, Eric, Lyssiotis, Costas A., Weerapana, Eranthie, Banerjee, Ruma
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690701/
https://ncbi.nlm.nih.gov/pubmed/31213529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009442
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