Structural basis for substrate selectivity and nucleophilic substitution mechanisms in human adenine phosphoribosyltransferase catalyzed reaction

The reversible adenine phosphoribosyltransferase enzyme (APRT) is essential for purine homeostasis in prokaryotes and eukaryotes. In humans, APRT (hAPRT) is the only enzyme known to produce AMP in cells from dietary adenine. APRT can also process adenine analogs, which are involved in plant developm...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Biol Chem
Main Authors: Ozeir, Mohammad, Huyet, Jessica, Burgevin, Marie-Claude, Pinson, Benoît, Chesney, Françoise, Remy, Jean-Marc, Siddiqi, Abdul Rauf, Lupoli, Roland, Pinon, Grégory, Saint-Marc, Christelle, Gibert, Jean-François, Morales, Renaud, Ceballos-Picot, Irène, Barouki, Robert, Daignan-Fornier, Bertrand, Olivier-Bandini, Anne, Augé, Franck, Nioche, Pierre
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2019
主題:
Editors' Picks
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690681/
https://ncbi.nlm.nih.gov/pubmed/31160323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009087
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍