Expression and function of Kv1.3 channel in malignant T cells in Sézary syndrome

The voltage-gated potassium channel Kv1.3 (KCNA3) is expressed by a subset of chronically activated memory T cells and plays an important role in their activation and proliferation. Here, we show that primary malignant T cells isolated from patients with Sézary syndrome (SS) express Kv1.3 and are se...

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發表在:Oncotarget
Main Authors: Hu, Tengpeng, Buus, Terkild Brink, Krejsgaard, Thorbjørn, Nansen, Anneline, Lundholt, Betina Kerstin, Spee, Pieter, Fredholm, Simon, Petersen, David Leander, Blümel, Edda, Gluud, Maria, Monteiro, Madalena N., Willerslev-Olsen, Andreas, Andersen, Mads Hald, Straten, Per thor, Met, Özcan, Stolearenco, Veronica, Fogh, Hanne, Gniadecki, Robert, Nastasi, Claudia, Litman, Thomas, Woetmann, Anders, Gjerdrum, Lise Mette Rahbek, Ødum, Niels
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2019
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690676/
https://ncbi.nlm.nih.gov/pubmed/31448055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27122
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