Dominant role of the α-chain in rejection of tumor cells bearing a specific alloantigen in TCRα transgenic mice and in in vitro experiments

Both TCRα and TCRβ types of T-cell receptors contribute to antigen recognition. However, some TCRs have chain centricity, which means that either the α-chain or the β-chain dictates the peptide–MHC complex specificity. Most earlier reports investigated the role of well-studied β-chains in antigen re...

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Udgivet i:Oncotarget
Main Authors: Zamkova, Maria, Kalinina, Anastasiya, Silaeva, Yuliya, Persiyantseva, Nadezhda, Bruter, Alexandra, Deikin, Alexey, Khromykh, Ludmila, Kazansky, Dmitry
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690675/
https://ncbi.nlm.nih.gov/pubmed/31448049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27093
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