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Metabolomic profiling reveals salivary hypotaurine as a potential early detection marker for medication-related osteonecrosis of the jaw

Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious adverse event of bone-modifying agents used to prevent bone complications in cancer patients with bone metastasis. Currently, early treatment is the only way to prevent further progression, as the pathogenesis of MRONJ has not...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Yatsuoka, Wakako, Ueno, Takao, Miyano, Kanako, Uezono, Yasuhito, Enomoto, Ayame, Kaneko, Miku, Ota, Sana, Soga, Tomoyoshi, Sugimoto, Masahiro, Ushijima, Toshikazu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690531/
https://ncbi.nlm.nih.gov/pubmed/31404085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0220712
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