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Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus
CRISPR-Cas systems are now widely used for genome editing and transcriptional regulation in diverse organisms. The compact and portable nature of class 2 single effector nucleases, such as Cas9 or Cas12, has facilitated directed genome modifications in plants, animals, and microbes. However, most CR...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6690032/ https://ncbi.nlm.nih.gov/pubmed/31341082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905421116 |
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