Sphingosine 1-Phosphate Receptors and Metabolic Enzymes as Druggable Targets for Brain Diseases

The central nervous system is characterized by a high content of sphingolipids and by a high diversity in terms of different structures. Stage- and cell-specific sphingolipid metabolism and expression are crucial for brain development and maintenance toward adult age. On the other hand, deep dysregu...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Grassi, Sara, Mauri, Laura, Prioni, Simona, Cabitta, Livia, Sonnino, Sandro, Prinetti, Alessandro, Giussani, Paola
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689979/
https://ncbi.nlm.nih.gov/pubmed/31427962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00807
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