Impact of a Complement Factor H Gene Variant on Renal Dysfunction, Cardiovascular Events, and Response to ACE Inhibitor Therapy in Type 2 Diabetes

Complement activation has been increasingly implicated in the pathogenesis of type 2 diabetes and its chronic complications. It is unknown whether complement factor H (CFH) genetic variants, which have been previously associated with complement-mediated organ damage likely due to inefficient complem...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Valoti, Elisabetta, Noris, Marina, Perna, Annalisa, Rurali, Erica, Gherardi, Giulia, Breno, Matteo, Parvanova Ilieva, Aneliya, Petrov Iliev, Ilian, Bossi, Antonio, Trevisan, Roberto, Dodesini, Alessandro Roberto, Ferrari, Silvia, Stucchi, Nadia, Benigni, Ariela, Remuzzi, Giuseppe, Ruggenenti, Piero
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689971/
https://ncbi.nlm.nih.gov/pubmed/31428128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00681
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