Paclitaxel-loaded biodegradable ROS-sensitive nanoparticles for cancer therapy

BACKGROUND: Reactive oxygen species (ROS), such as hydrogen peroxide and superoxide, trigger biodegradation of polymer-based nanoparticles (NPs) bearing pinacol-type boronic ester groups. These NPs may selectively release their cargo, in this case paclitaxel (PTX), at the high levels of ROS present...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Pandya, Abhilash D, Jäger, Eliézer, Bagheri Fam, Shahla, Höcherl, Anita, Jäger, Alessandro, Sincari, Vladimir, Nyström, Bo, Štěpánek, Petr, Skotland, Tore, Sandvig, Kirsten, Hrubý, Martin, Mælandsmo, Gunhild M
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689768/
https://ncbi.nlm.nih.gov/pubmed/31496685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S208938
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