mTORC1/rpS6 signaling complex modifies BTB transport function: an in vivo study using the adjudin model

Studies have shown that the mTORC1/rpS6 signaling cascade regulates Sertoli cell blood-testis barrier (BTB) dynamics. For instance, specific inhibition of mTORC1 by treating Sertoli cells with rapamycin promotes the Sertoli cell barrier, making it “tighter.” However, activation of mTORC1 by overexpr...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Yan, Ming, Li, Linxi, Mao, Baiping, Li, Huitao, Li, Stephen Y. T., Mruk, Dolores, Silvestrini, Bruno, Lian, Qingquan, Ge, Renshan, Cheng, C. Yan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689739/
https://ncbi.nlm.nih.gov/pubmed/31112404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00553.2018
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