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mTORC1/rpS6 signaling complex modifies BTB transport function: an in vivo study using the adjudin model
Studies have shown that the mTORC1/rpS6 signaling cascade regulates Sertoli cell blood-testis barrier (BTB) dynamics. For instance, specific inhibition of mTORC1 by treating Sertoli cells with rapamycin promotes the Sertoli cell barrier, making it “tighter.” However, activation of mTORC1 by overexpr...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Am J Physiol Endocrinol Metab |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Physiological Society
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6689739/ https://ncbi.nlm.nih.gov/pubmed/31112404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00553.2018 |
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