GM-CSF and CXCR4 Define a T Helper Cell Signature in Multiple Sclerosis

Cytokine dysregulation is a central driver of chronic inflammatory diseases such as multiple sclerosis (MS). Here we sought to determine the characteristic cellular and cytokine polarization profile in patients with relapsing-remitting multiple sclerosis (RRMS) by high-dimensional single-cell mass c...

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Publicat a:Nat Med
Autors principals: Galli, Edoardo, Hartmann, Felix J., Schreiner, Bettina, Ingelfinger, Florian, Arvaniti, Eirini, Diebold, Martin, Mrdjen, Dunja, van der Meer, Franziska, Krieg, Carsten, Al Nimer, Faiez, Sanderson, Nicholas, Stadelmann, Christine, Khademi, Mohsen, Piehl, Fredrik, Claassen, Manfred, Derfuss, Tobias, Olsson, Tomas, Becher, Burkhard
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689469/
https://ncbi.nlm.nih.gov/pubmed/31332391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-019-0521-4
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