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New pathologic mechanisms in nucleotide repeat expansion disorders

Tandem microsatellite repeats are common throughout the human genome and intrinsically unstable, exhibiting expansions and contractions both somatically and across generations. Instability in a small subset of these repeats are currently linked to human disease, although recent findings suggest more...

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Библиографические подробности
Опубликовано в: :Neurobiol Dis
Главные авторы: Rodriguez, C.M., Todd, P.K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689435/
https://ncbi.nlm.nih.gov/pubmed/31229686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.104515
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