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Targeted complement inhibition salvages stressed neurons and inhibits neuroinflammation after stroke in mice

Ischemic stroke results from the interruption of blood flow to the brain resulting in long-term motor and cognitive neurological deficits, and it is a leading cause of death and disability. Current interventions focus on the restoration of blood flow to limit neuronal death, but these treatments hav...

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Bibliografiske detaljer
Udgivet i:Sci Transl Med
Main Authors: Alawieh, Ali, Langley, E. Farris, Tomlinson, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689196/
https://ncbi.nlm.nih.gov/pubmed/29769288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aao6459
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