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Construction of a synthetic pathway for the production of 1,3-propanediol from glucose

In this work, we describe the construction of a synthetic metabolic pathway enabling direct biosynthesis of 1,3-propanediol (PDO) from glucose via the Krebs cycle intermediate malate. This non-natural pathway extends a previously published synthetic pathway for the synthesis of (L)-2,4-dihydroxybuty...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Frazão, Cláudio J. R., Trichez, Débora, Serrano-Bataille, Hélène, Dagkesamanskaia, Adilia, Topham, Christopher M., Walther, Thomas, François, Jean Marie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689062/
https://ncbi.nlm.nih.gov/pubmed/31399628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48091-7
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