The Hippo effector TAZ promotes cancer stemness by transcriptional activation of SOX2 in head neck squamous cell carcinoma

The Hippo-TAZ signaling has emerged as a fundamental regulator underlying cancer stem cells (CSCs) stemness which intricately associates with local recurrence and metastatic spreading in head neck squamous cell carcinoma (HNSCC). However, the precise downstream targets of TAZ responsible for HNSCC C...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Li, Jin, Li, Zhongwu, Wu, Yaping, Wang, Yanling, Wang, Dongmiao, Zhang, Wei, Yuan, Hua, Ye, Jinhai, Song, Xiaomeng, Yang, Jianrong, Jiang, Hongbing, Cheng, Jie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689034/
https://ncbi.nlm.nih.gov/pubmed/31399556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1838-0
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