The Hippo effector TAZ promotes cancer stemness by transcriptional activation of SOX2 in head neck squamous cell carcinoma

The Hippo-TAZ signaling has emerged as a fundamental regulator underlying cancer stem cells (CSCs) stemness which intricately associates with local recurrence and metastatic spreading in head neck squamous cell carcinoma (HNSCC). However, the precise downstream targets of TAZ responsible for HNSCC C...

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Опубликовано в: :Cell Death Dis
Главные авторы: Li, Jin, Li, Zhongwu, Wu, Yaping, Wang, Yanling, Wang, Dongmiao, Zhang, Wei, Yuan, Hua, Ye, Jinhai, Song, Xiaomeng, Yang, Jianrong, Jiang, Hongbing, Cheng, Jie
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689034/
https://ncbi.nlm.nih.gov/pubmed/31399556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1838-0
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