The Hippo effector TAZ promotes cancer stemness by transcriptional activation of SOX2 in head neck squamous cell carcinoma

The Hippo-TAZ signaling has emerged as a fundamental regulator underlying cancer stem cells (CSCs) stemness which intricately associates with local recurrence and metastatic spreading in head neck squamous cell carcinoma (HNSCC). However, the precise downstream targets of TAZ responsible for HNSCC C...

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Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Li, Jin, Li, Zhongwu, Wu, Yaping, Wang, Yanling, Wang, Dongmiao, Zhang, Wei, Yuan, Hua, Ye, Jinhai, Song, Xiaomeng, Yang, Jianrong, Jiang, Hongbing, Cheng, Jie
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689034/
https://ncbi.nlm.nih.gov/pubmed/31399556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1838-0
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