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Crystal structures of Hsp104 N-terminal domains from Saccharomyces cerevisiae and Candida albicans suggest the mechanism for the function of Hsp104 in dissolving prions

Hsp104 is a yeast member of the Hsp100 family which functions as a molecular chaperone to disaggregate misfolded polypeptides. To understand the mechanism by which the Hsp104 N-terminal domain (NTD) interacts with its peptide substrates, crystal structures of the Hsp104 NTDs from Saccharomyces cerev...

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Bibliografische gegevens
Gepubliceerd in:Acta Crystallogr D Struct Biol
Hoofdauteurs: Wang, Peng, Li, Jingzhi, Weaver, Clarissa, Lucius, Aaron, Sha, Bingdong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: International Union of Crystallography 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688567/
https://ncbi.nlm.nih.gov/pubmed/28375147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798317002662
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