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Combination therapy of brain radiotherapy and EGFR-TKIs is more effective than TKIs alone for EGFR-mutant lung adenocarcinoma patients with asymptomatic brain metastasis

BACKGROUND: The treatment strategy for brain metastasis (BM) in patients with epidermal growth factor receptor (EGFR) -mutant lung adenocarcinoma (LAC) remains controversial. In the present study, we compared the efficacy of brain radiotherapy (RT) in combination with tyrosine kinase inhibitors (TKI...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Chen, Yanxin, Wei, Jianping, Cai, Jing, Liu, Anwen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688250/
https://ncbi.nlm.nih.gov/pubmed/31399067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6005-6
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