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Microsampling Capillary Electrophoresis Mass Spectrometry Enables Single-cell Proteomics in Complex Tissues: Developing Cell Clones in Live Xenopus laevis and Zebrafish Embryos

Label-free single-cell proteomics by mass spectrometry (MS) is currently incompatible with complex tissues without requiring cell culturing, single-cell dissection, or tissue dissociation. We here report the first example of label-free single-cell MS-based proteomics directly in single cells in live...

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Vydáno v:Anal Chem
Hlavní autoři: Lombard-Banek, Camille, Moody, Sally A., Manzini, M. Chiara, Nemes, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688183/
https://ncbi.nlm.nih.gov/pubmed/30827088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b00345
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