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The Role of Glypican-3 in Regulating Wnt, YAP, and Hedgehog in Liver Cancer

Glypican-3 (GPC3) is a cell-surface glycoprotein consisting of heparan sulfate glycosaminoglycan chains and an inner protein core. It has important functions in cellular signaling including cell growth, embryogenesis, and differentiation. GPC3 has been linked to hepatocellular carcinoma and a few ot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Kolluri, Aarti, Ho, Mitchell
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688162/
https://ncbi.nlm.nih.gov/pubmed/31428581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00708
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