Comprehensive analysis of EGFR T790M detection by ddPCR and ARMS-PCR and the effect of mutant abundance on the efficacy of osimertinib in NSCLC patients

BACKGROUND: Patients with non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations often develop systemic disease progression during treatment with EGFR-tyrosine kinase inhibitors (TKIs). Droplet digital polymerase chain reaction (ddPCR) and amplification refrac...

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Detalhes bibliográficos
Publicado no:J Thorac Dis
Main Authors: Li, Yue, Xu, Yuxia, Wu, Xiaoyan, He, Caiyun, Liu, Qing, Wang, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688018/
https://ncbi.nlm.nih.gov/pubmed/31463130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2019.07.42
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