Clinical importance of Bcl-2-like 11 deletion polymorphism in idiopathic pulmonary fibrosis

BACKGROUND: Reactive oxygen species (ROS) can play a role in the pathogenesis of Idiopathic Pulmonary Fibrosis (IPF) by contributing to epithelial damage. Bcl-2-like 11 (BIM) is involved in the generation of ROS via forkhead box O3 (FOXO3), and a BIM deletion polymorphism related to apoptosis has be...

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Publicat a:J Thorac Dis
Autors principals: Isobe, Kazutoshi, Issiki, Takuma, Sakamoto, Susumu, Sano, Go, Takai, Yujiro, Tochigi, Naobumi, Homma, Sakae
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688017/
https://ncbi.nlm.nih.gov/pubmed/31463128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2019.07.25
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