Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study

DNA methylation acts at the interface of genetic and environmental factors relevant for autism spectrum disorder (ASD). Placenta, normally discarded at birth, is a potentially rich source of DNA methylation patterns predictive of ASD in the child. Here, we performed whole methylome analyses of place...

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Pubblicato in:Hum Mol Genet
Autori principali: Zhu, Yihui, Mordaunt, Charles E, Yasui, Dag H, Marathe, Ria, Coulson, Rochelle L, Dunaway, Keith W, Jianu, Julia M, Walker, Cheryl K, Ozonoff, Sally, Hertz-Picciotto, Irva, Schmidt, Rebecca J, LaSalle, Janine M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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General Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687952/
https://ncbi.nlm.nih.gov/pubmed/31009952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz084
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