Complementation of Wild-Type and Drug-Resistant Hepatitis B Virus Genomes to Maintain Viral Replication and Rescue Virion Production under Nucleos(t)ide Analogs

As the open reading frames of hepatitis B virus (HBV) genomes are overlapping, resistance mutations (MTs) in HBV polymerase may result in stop codon MTs in hepatitis B surface proteins, which are usually detected as a mixed population with wild-type (WT) HBV. The question was raised how the coexiste...

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Vydáno v:Virol Sin
Hlavní autoři: Wu, Chunchen, Li, Baolin, Zhang, Xiaoyong, Zhao, Kaitao, Chen, Yingshan, Yuan, Yifei, Liu, Yan, Chen, Rongjuan, Xu, Dongping, Chen, Xinwen, Lu, Mengji
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Singapore 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687792/
https://ncbi.nlm.nih.gov/pubmed/31218588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-019-00143-y
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