Keap1/Nrf2 Signaling: A New Player in Thyroid Pathophysiology and Thyroid Cancer

The Keap1/Nrf2 pathway is a key mediator of general redox and tissue-specific homeostasis. It also exerts a dual role in cancer, by preventing cell transformation of normal cells but promoting aggressiveness, and drug resistance of malignant ones. Although Nrf2 is well-studied in other tissues, its...

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Bibliografiske detaljer
Udgivet i:Front Endocrinol (Lausanne)
Main Authors: Renaud, Cedric O., Ziros, Panos G., Chartoumpekis, Dionysios V., Bongiovanni, Massimo, Sykiotis, Gerasimos P.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Endocrinology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687762/
https://ncbi.nlm.nih.gov/pubmed/31428048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00510
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