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Mechanically-induced GDF15 Secretion by Periodontal Ligament Fibroblasts Regulates Osteogenic Transcription

The alveolar bone provides structural support against compressive and tensile forces generated during mastication as well as during orthodontic treatment. To avoid abnormal alveolar bone resorption and tooth loss, a balanced bone turnover by bone-degrading osteoclasts and bone-generating osteoblasts...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Symmank, Judit, Zimmermann, Sarah, Goldschmitt, Jutta, Schiegnitz, Eik, Wolf, Michael, Wehrbein, Heinrich, Jacobs, Collin
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687747/
https://ncbi.nlm.nih.gov/pubmed/31395909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47639-x
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