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Characterization of large deletions of the MECP2 gene in Rett syndrome patients by gene dosage analysis

BACKGROUND: Rett syndrome (RTT) is a developmental disorder with an early onset and X‐linked dominant inheritance pattern. It is first recognized in infancy and is seen almost always in girls, but it may be seen in boys on rare occasions. Typical RTT is caused by de novo mutations of the gene MECP2...

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Библиографические подробности
Опубликовано в: :Mol Genet Genomic Med
Главные авторы: Vidal, Silvia, Pascual‐Alonso, Ainhoa, Rabaza‐Gairí, Marc, Gerotina, Edgar, Brandi, Nuria, Pacheco, Paola, Xiol, Clara, Pineda, Mercè, Armstrong, Judith
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687651/
https://ncbi.nlm.nih.gov/pubmed/31206249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.793
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