Haplotype analysis of SERPINE1 gene: Risk for aneurysmal subarachnoid hemorrhage and clinical outcomes

BACKGROUND: Aneurysmal subarachnoid hemorrhage (aSAH) has high fatality and permanent disability rates due to the severe damage to brain cells and inflammation. The SERPINE1 gene that encodes PAI‐1 for the regulation of tissue plasminogen activator is considered an important therapeutic target for a...

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Vydáno v:Mol Genet Genomic Med
Hlavní autoři: Lin, Mingkuan, Griessenauer, Christoph J., Starke, Robert M., Tubbs, R. Shane, Shoja, Mohammadali M., Foreman, Paul M., Vyas, Nilesh A., Walters, Beverly C., Harrigan, Mark R., Hendrix, Philipp, Fisher, Winfield S., Pittet, Jean‐Francois, Mathru, Mali, Lipsky, Robert H.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687628/
https://ncbi.nlm.nih.gov/pubmed/31268630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.737
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