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Click and photo-release dual-functional nucleic acid nanostructures

We functionalize nucleic acid nanostructures with click chemistry (for attachment of cargos) and a photocleavable linker (for release). We demonstrate cargo attachment using a fluorescein dye and release using UV trigger from an RNA three-way junction, a DNA star motif and a DNA tetrahedron. Such mu...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Valsangkar, Vibhav A., Chandrasekaran, Arun Richard, Zhuo, Lifeng, Mao, Song, Lee, Gohwoon, Kizer, Megan, Wang, Xing, Halvorsen, Ken, Sheng, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687541/
https://ncbi.nlm.nih.gov/pubmed/31353371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc03806j
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