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An outlook on using serial femtosecond crystallography in drug discovery

INTRODUCTION: X-ray crystallography has made important contributions to modern drug development but its application to many important drug targets has been extremely challenging. The recent emergence of X-ray free electron lasers (XFELs) and advancements in serial femtosecond crystallography (SFX) h...

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Detalhes bibliográficos
Publicado no:Expert Opin Drug Discov
Main Authors: Mishin, Alexey, Gusach, Anastasiia, Luginina, Aleksandra, Marin, Egor, Borshchevskiy, Valentin, Cherezov, Vadim
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687307/
https://ncbi.nlm.nih.gov/pubmed/31184514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17460441.2019.1626822
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