The current state of animal models and genomic approaches towards identifying and validating molecular determinants of Mycobacterium tuberculosis infection and tuberculosis disease

Animal models are important in understanding both the pathogenesis of and immunity to tuberculosis (TB). Unfortunately, we are beginning to understand that no animal model perfectly recapitulates the human TB syndrome, which encompasses numerous different stages. Furthermore, Mycobacterium tuberculo...

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Bibliografiske detaljer
Udgivet i:Pathog Dis
Main Authors: Bucsan, Allison N, Mehra, Smriti, Khader, Shabaana A, Kaushal, Deepak
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Minireview
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687098/
https://ncbi.nlm.nih.gov/pubmed/31381766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftz037
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