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Molecular insights into the differences in anti-inflammatory activities of green tea catechins on IL-1β signaling in rheumatoid arthritis synovial fibroblasts

In this study, we found that catechins found in green tea (EGCG, EGC, and EC) differentially interfere with the IL-1β signaling pathway which regulates the expression of pro-inflammatory mediators (IL-6 and IL-8) and Cox-2 in primary human rheumatoid arthritis synovial fibroblasts (RASFs). EGCG and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Appl Pharmacol
Hauptverfasser: Fechtner, Sabrina, Singh, Anil, Chourasia, Mukesh, Ahmed, Salahuddin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686859/
https://ncbi.nlm.nih.gov/pubmed/28532672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2017.05.016
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