Efficacy of administered mesenchymal stem cells in the initiation and co‐ordination of repair processes by resident disc cells in an ovine (Ovis aries) large destabilizing lesion model of experimental disc degeneration

BACKGROUND: Forty percent of low back pain cases are due to intervertebral disc degeneration (IVDD), with mesenchymal stem cells (MSCs) a reported treatment. We utilized an ovine IVDD model and intradiscal heterologous MSCs to determine therapeutic efficacy at different stages of IVDD. METHODOLOGY:...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JOR Spine
Prif Awduron: Shu, Cindy C., Dart, Andrew, Bell, Robin, Dart, Christina, Clarke, Elizabeth, Smith, Margaret M., Little, Christopher B., Melrose, James
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley & Sons, Inc. 2018
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686814/
https://ncbi.nlm.nih.gov/pubmed/31463452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1037
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