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Motor neuron biology and disease: A current perspective on infantile-onset spinal muscular atrophy

Infantile-onset spinal muscular atrophy (SMA) is a prototypical disease in which to investigate selective neurodegenerative phenotypes. Caused by low levels of the ubiquitously expressed Survival Motor Neuron (SMN) protein, the disease mainly targets the spinal motor neurons. This selective phenotyp...

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Pubblicato in:Future Neurol
Autori principali: Jha, Narendra N., Kim, Jeong-Ki, Monani, Umrao R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686682/
https://ncbi.nlm.nih.gov/pubmed/31396020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fnl-2018-0008
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