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Targeting CYP4A attenuates hepatic steatosis in a novel multicellular organotypic liver model

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) begins as simple hepatic steatosis, but further progress to chronic liver diseases results in severe liver damage and hepatic failure. However, therapeutic options are scarce due to the lack of reliable human in vitro liver models for understandi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Eng
Päätekijät: Ryu, Jae-Sung, Lee, Minji, Mun, Seon Ju, Hong, Sin-Hyoung, Lee, Ho-Joon, Ahn, Hyo-Suk, Chung, Kyung-Sook, Kim, Gun-Hwa, Son, Myung Jin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686528/
https://ncbi.nlm.nih.gov/pubmed/31406506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0198-8
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