SNORD89 promotes stemness phenotype of ovarian cancer cells by regulating Notch1-c-Myc pathway

BACKGROUND: Ovarian cancer is the leading cause of death in gynecological cancer. Cancer stem cells (CSCs) contribute to the occurrence, progression and resistance. Small nucleolar RNAs (SnoRNAs), a class of small molecule non-coding RNA, involve in the cancer cell stemness and tumorigenesis. METHOD...

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Vydáno v:J Transl Med
Hlavní autoři: Zhu, Wenjing, Niu, Jumin, He, Miao, Zhang, Liwen, Lv, Xuemei, Liu, Fangxiao, Jiang, Longyang, Zhang, Jing, Yu, Zhaojin, Zhao, Lin, Bi, Jia, Yan, Yuanyuan, Wei, Qian, Huo, Hong, Fan, Yue, Chen, Yuzong, Ding, Jian, Wei, Minjie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686521/
https://ncbi.nlm.nih.gov/pubmed/31395064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-2005-1
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