Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson’s disease and multiple system atrophy

BACKGROUND: Parkinson’s disease (PD) is a neurodegenerative disorder whose diagnosis is often challenging because symptoms may overlap with neurodegenerative parkinsonisms. PD is characterized by intraneuronal accumulation of abnormal α-synuclein in brainstem while neurodegenerative parkinsonisms mi...

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Published in:Transl Neurodegener
Main Authors: De Luca, Chiara Maria Giulia, Elia, Antonio Emanuele, Portaleone, Sara Maria, Cazzaniga, Federico Angelo, Rossi, Martina, Bistaffa, Edoardo, De Cecco, Elena, Narkiewicz, Joanna, Salzano, Giulia, Carletta, Olga, Romito, Luigi, Devigili, Grazia, Soliveri, Paola, Tiraboschi, Pietro, Legname, Giuseppe, Tagliavini, Fabrizio, Eleopra, Roberto, Giaccone, Giorgio, Moda, Fabio
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686411/
https://ncbi.nlm.nih.gov/pubmed/31406572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-019-0164-x
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