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MiR-135-5p promotes osteoblast differentiation by targeting HIF1AN in MC3T3-E1 cells

BACKGROUND: MicroRNAs (miRNAs or miRs) serve crucial roles in the progression of osteoporosis. This study investigated the role and specific molecular mechanism of miR-135-5p in regulating osteoblast differentiation and calcification. METHODS: Bone morphogenetic protein 2 (BMP2) was employed to inte...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Yin, Nuo, Zhu, Longzhang, Ding, Liang, Yuan, Junjie, Du, Li, Pan, Mingmang, Xue, Feng, Xiao, Haijun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686269/
https://ncbi.nlm.nih.gov/pubmed/31410089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-019-0177-6
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