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The strange case of AMPK and cancer: Dr Jekyll or Mr Hyde?(†)
The AMP-activated protein kinase (AMPK) acts as a cellular energy sensor. Once switched on by increases in cellular AMP : ATP ratios, it acts to restore energy homeostasis by switching on catabolic pathways while switching off cell growth and proliferation. The canonical AMP-dependent mechanism of a...
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| Publié dans: | Open Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Royal Society
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6685927/ https://ncbi.nlm.nih.gov/pubmed/31288625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190099 |
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