HIV infection modulates IL-1β response to LPS stimulation through a TLR4-NLRP3 pathway in human liver macrophages

IL-1β is an important mediator of innate inflammatory responses and has been shown to contribute to liver injury in a number of etiologies. HIV patients have increased necroinflammation and more rapid fibrosis progression in chronic liver injury compared to non-HIV-infected patients. As the resident...

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Udgivet i:J Leukoc Biol
Main Authors: Zhang, Lumin, Mosoian, Arevik, Schwartz, Myron E., Florman, Sander S., Gunasekaran, Ganesh, Schiano, Thomas, Fiel, M. Isabel, Jiang, Wei, Shen, Qi, Branch, Andrea D., Bansal, Meena B.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685708/
https://ncbi.nlm.nih.gov/pubmed/30776150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4A1018-381R
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