High tumoral PD-L1 expression and low PD-1(+) or CD8(+) tumor-infiltrating lymphocytes are predictive of a poor prognosis in primary diffuse large B-cell lymphoma of the central nervous system

We investigated the clinicopathological role of the PD-1/PD-L1 pathway in primary diffuse large B-cell lymphoma of the central nervous system (PCNS-DLBCL) arising in the immune-privileged site. PD-L1 immunostaining of ≥30% of tumor cells was defined as tPD-L1+, and PD-L1 immunostaining of ≥30% of to...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Kim, Sehui, Nam, Soo Jeong, Park, Changhee, Kwon, Dohee, Yim, Jeemin, Song, Seung Geun, Ock, Chan-Young, Kim, Young A, Park, Sung Hye, Kim, Tae Min, Jeon, Yoon Kyung
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685509/
https://ncbi.nlm.nih.gov/pubmed/31428525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1626653
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